Solid-phase extraction (SPE) is a sample pretreatment technique developed in recent years. It combines liquid-solid extraction columns and liquid chromatography, and is mainly used for sample separation, purification, and concentration. Compared with traditional liquid-liquid extraction methods, it can improve analyte recovery, more effectively separate analytes from interfering components, reduce sample pretreatment processes, and is simple, time-saving, and labor-saving. It is widely used in pharmaceuticals, food, environmental protection, commodity inspection, and chemical industries.